EURL ECVAM Releases its Strategy for the Use of Alternative Methods for Acute Systemic Toxicity Testing
The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Center recently released a strategy on how to replace, reduce and refine the use of animals for acute mammalian systemic toxicity testing. Based on an assessment of regulatory needs across sectors and the scientific state-of-the art in the area, the strategy sets out strategic aims and associated objectives that are expected to deliver a significant 3Rs impact. In addition to gaining a better understanding of the mechanisms by which a substance can cause an acute systemically toxic effect, EURL ECVAM also recommends exploring methods by which the requirement for systemic toxicity testing could be waived for a substance. For additional information on EURL ECVAM's recommendation and a link to the pdf download of the recommendation, please follow the link above.