The European Partnership for Alternative Approaches to Animal Testing (EPAA) is proud to launch this call to apply for the 2016 3Rs Science Prize. This year, the EPAA will grant a Prize for already achieved research, or a project already at the completion stage with outstanding results. The EPAA 3Rs Science Prize is granted every other year to a scientist whose contribution to 3Rs is found to be outstanding. Its purpose is to promote such positive contributions from industry or academia and to encourage more scientists in the future to focus their research to the 3Rs goals. Scientists working on methods for safety and/or quality testing and applying the 3Rs (replacement, reduction or refinement of animal testing) to those methods may apply for this prize.