Physiological relevance is a key parameter to improve predictivity of cell-based assays in drug discovery and toxicity testing for compound. The continually rising numbers of compound failures and increasing costs of drug and substance development are fostering the use of biologically more complex cell models from target identification to safety testing in substance development. Conventional 2D culture conditions are highly limited as native tissue morphology and cell composition is not properly reflected. To create tissue-specific structures and function in vitro, cell models have to be translated into the third dimension.
Therefore, 3D cell culture technologies and associated analytical tools are essential for basic and pharmaceutical research as well as for the evaluation of chemicals and cosmetics.
The conference covers the newest developments in the key areas of 3D cell culture technologies. This comprises advanced 3D cell culture models for efficacy and safety studies, enabling technologies to create and analyze biological reactions as well as their successful implementation in compound de-risking.